Journal Publications

Cummings, M., Massey, K., Mappa, G., Wilkinson, N., Hutson, R., Munot, S., Saidi, S., Nugent, D., Broadhead, T., Wright, A. I., Barber, S., Nicolaou, A., Orsi, N. M. (2018). Integrated eicosanoid lipidomics and gene expression in endometrial cancer: prognostic significance of 15-hydroxyprostaglandin dehydrogenase and 5-lipoxygenase. Submitted to: Journal of Pathology.


Clarke, E. L., Brettle, D., Sykes, A., Wright, A. I., Boden, A., Treanor, D. E. (2018). Development and evaluation of a novel point-of-use quality assurance tool for digital pathology. Accepted for Publication in: Archives of Pathology.


Hutchins, G. G. A., Treanor, D. E., Wright, A. I., Handley, K., Magill, L., Tinkler-Hundal, E., Southward, K., Seymour, M., Kerr, D., Gray, R., Quirke, P., (2017). Intra-tumoural stromal morphometry predicts disease recurrence but not response to 5-flurouracil – results from the QUASAR trial of colorectal cancer. Histopathology. 2018; 72(3); pp 391-404; doi:10.1111/his.13326


Hale, M. D., Nankivell, M., Hutchins, G. G., Stenning, S. P., Langley, R. E., Mueller, W., West, N. P., Wright, A. I., Treanor, D. E., Hewitt, L. C., Allum, W. H., Cunningham, D., Hayden, J. D., Grabsch, H. I. (2016). Biopsy proportion of tumour predicts pathological tumour response and benefit from chemotherapy in resectable oesophageal carcinoma - Results from the UK MRC OE02 trial. Oncotarget. 7(47); doi:10.18632/oncotarget.12723


Wright, A. I., Magee, D. R., Quirke, P., Treanor, D. E. (2016). Incorporating Local and Global Context for Better Automated Analysis of Colorectal Cancer on Digital Pathology Slides. 20th Conference on Medical Image Understanding and Analysis (MIUA 2016) Proc Comp Science. Vol 90, pp 125-131; doi:10.1016/j.procs.2016.07.034


Panayiotou, H. R., Orsi, N., Wright, A. I., Winder, M., Cummings, M. (2015). The Prognostic Significance of Tumour/Stroma Ratio in Endometrial Adenocarcinoma. Journal of Reproductive Sciences. 2015; 22 ():119A-119A


Gray, A., Wright, A. I., Jackson, P., Hale, M., Treanor, D. E. (2015). Quantification of Histochemical Stains Using Whole Slide Imaging: Development of a Method and Demonstration of Its Usefulness in Laboratory Quality Control. Journal of Clinical Pathology. 2015;68(3):192-199


Wright, A. I., Magee, D. R., Quirke, P., Treanor, D. E. (2015). Propsector: A web-based tool for rapid acquisition of gold standard data for pathology research and image analysis. Journal of Pathology Informatics. 2015;6:21


Wright, A. I., Grabsch, H. I., Treanor, D. E. (2015). RandomSpot: A web-based tool for systematic random sampling of virtual slides. Journal of Pathology Informatics. 2015;6:8


Sethi, N., Wright, A. I., Wood, H., Rabbitts, P. (2014). MicroRNAs and head and neck cancer: Reviewing the first decade of research. European Journal of Cancer. 50(15), 2619-2635


Wright, A. I., Magee, D., R., Quirke, P., Treanor, D. (2014). Towards automatic patient selection for chemotherapy in colorectal cancer trials.* Proc. SPIE 9041, Medical Imaging 2014: Digital Pathology, 90410A (March 20, 2014); doi:10.1117/12.2043220


Hale, M. D., Nankivell, M. G., Mueller, W., West, N. P., Stenning, S. P., Wright, A. I., Treanor, D. E., Langley, R. E., Ward, L. C., Allum, W. H., Cunningham, D., Hayden, J. D., Grabsch, H. I. (2014). The relationship between tumour cell density in the pre-treatment biopsy and survival after chemotherapy in OE02 trial oesophageal cancer patients. Journal of Clinical Oncology. 32(3), 49-49.


Palmer, T., Georgiades, I., Treanor, D., Wright, A. I., et al. (2013). Improved tissue sections for medical liver biopsies: a comparison of 16 vs 18 g biopsy needles using digital pathology. J Clin Pathol. 67(5), 415-419 doi:10.1136/jclinpath-2013-201954


Wu, Y., Grabsch, H., Ivanova, T., Tan, I. B., Murray, J., Ooi, C. H., Wright, A. I., West, N. P., Hutchins, G. G. A., Wu, J., Lee, M., Koo, J. H., Yeoh, K. G., van Grieken, N., Ystra, B., Rha, S. Y., Ajani, J. A., Cheong, J. H., Noh, S. H., Lim, K. H., Boussioutas, A., Lee, J. S.& Tan, P. (2013). Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer. Gut, 62(8), 1100-1111.


Wright, A., Lyttleton, O., Lewis, P., Quirke, P. & Treanor, D., 2011. The tissue microarray data exchange specification: Extending TMA DES to provide flexible scoring and incorporate virtual slides. J Pathol Inform, 2(1), p.15.


Lyttleton, O., Wright, A., Treanor, D. & Lewis, P., 2011. Using XML to encode TMA DES metadata. J Pathol Inform, 2(1), p.40.


Lyttleton, O., Wright, A., Treanor, D., Quirke, P., et al., 2011. Extending the tissue microarray data exchange specification for inclusion of data analysis results. J Pathol Inform, 2(1), p.17.


*Recipient of Best Student Paper Award

Conference Presentations

Stone, R., Wright, A., Clarke, E., Hanby, A., Treanor, D., Hogg, D., Bulpitt, A. (2018) Decoupled neural networks for classification of breast microscopy images . To be presented at: Medical Imaging Summer School 2018. Favignana, Sicily.


Clarke, E., Hindley, A., Wright, A. (2018) An ‘Interactive Human Body: A pathology public engagement tool.*** Presented at: Pathological Society Winter School 2018 . Hilton Victoria, London, UK.


Verschueren, N., Hewitt, L. C., Fazzil, G., Wright, A., Hayden, J. D., Hutchins, G. G., Grabsch, H. I. (2016) Intratumoural Nerve Fibre Detection in Oesophageal Cancer - a Novel Prognostic Feature After Neoadjuvant Therapy. Presented at: 205th Meeting of the Pathological Society of Great Britain & Ireland. University College London, UK.


King, H., Payne, H., Brend, T., Patel, A., Wright A, Englu, T., Stead, L., Wurdak, H., Short, S. C. (2015) Radioresistance in glioma stem cells driven by Rad51 dependent homologous recombination repair. Presented at: American Association for Cancer Research - 106th Annual Meeting 2015. Philadelphia, PA, US.


Wright A (2015) Automated analysis of virtual slides: are we nearly there yet? Presented at: Leeds Institutes of Molecular Medicine Postgraduate Symposium. Leeds, UK.


Kidanu D, McCarthy R, Cummings M, Wright A, Roberts N, Orsi N. (2014) Does superovulation affect ovarian perifollicular vascularity? A murine 3D reconstruction and 2D microvessel analysis pilot study . Presented at: Gastrointestinal Congress of the American Society of Clinical Oncology. Chicago, IL, US.


Hale M D, Nankivell M G, Stenning S P, Langley R E, Mueller W, West N P, Wright A I, Treanor D E, Hewitt L C, Allum W H, Cunningham D, Hayden J D, Grabsch H I (2014) Tumour cell density in the pre-treatment biopsy predicts benefit from chemotherapy in patients with resectable oesophageal carcinoma recruited into the OE02 trial. Presented at: 2014 NCRI Cancer Conference. Liverpool, UK.


Earle S, Aoyama T, Wright A I, Treanor D E, Miyagi Y, Hewitt L C, Hayden J D, Yoshikawa T, Thygessen H I, Grabsch H I (2014) Prognostic and predictive value of tumour infiltrating immune cells in stage II/III Japanese gastric cancer . Presented at: Gastrointestinal Congress of the American Society of Clinical Oncology. Chicago, IL, US.


Wright, A. I., Magee, D., R., Quirke, P., Treanor, D. (2014). Towards automatic patient selection for chemotherapy in colorectal cancer trials. . Presented at: SPIE Medical Imaging. San Diego, CA, US.


Hale M D, Nankivell M G, Mueller W, West N P, Stenning S P, Wright A I, Treanor D E, Langley R E, Ward L C, Allum W H, Cunningham D, Hayden J D, Grabsch H I (2013) The relationship between tumour cell density in the pre-treatment biopsy and survival after chemotherapy in OE02 trial oesophageal cancer patients. Presented at: Gastrointestinal Congress of the American Society of Clinical Oncology. San Francisco, CA, US.


Gray, A., Wright A, Jackson, P., Hale, M., Treanor, D. (2013). Quality con- trol of histochemical stains: repeatable and objective quantification using virtual slides. Presented at: Pathology Visions. San Antonio, US.


Wright A, Treanor D. (2013). Automatic analysis to calculate the tumour:stroma ratio in colorectal cancer. Presented at: Leeds Institute of Molecular Medicine postgraduate research symposium. University of Leeds, UK.


Aziz AK, Wright A, Treanor D, Mehta SP, Ward LC, Grabsch HI (2013). No Evidence of a Chemotherapy Induced Immune Cell Response in Oesophageal Cancer Tissue. Presented at: Joint Meeting of the Pathological Society of Great Britain and Ireland and the Dutch Pathological Society. University of Utrecht, The Netherlands.


Wright A, Hutchins G, West N, Toh E, Magee D, Quirke P, Treanor D (2012). An automatic approach to improving patient selection for chemotherapy. Presented at: Showcase 2012 - The 3rd annual University of Leeds postgraduate research conference. University of Leeds, UK.


Wright A, Coe A, Dattani M, Toh E, Hutchins G, West N, Grabsch H, Magee D, Quirke P, Treanor D (2012). Automatic Image Analysis to Calculate the Cancer:Stroma Ratio in Colorectal Cancer. Presented at: Joint Meeting of the Pathological Society of Great Britain and Ireland and the Dutch Pathological Society. University of Sheffield, UK.


Lovett S, Wright A, Treanor D, Ward L C, Grabsch H I (2012). The Presence of Macrophages is Related to Tumour Cell Density in Gastric Cancer - A Pilot Study Comparing Automated Image Analysis with Subjective Scoring in Full Sections and Virtual Tissue Cores. Presented at: Joint Meeting of the Pathological Society of Great Britain and Ireland and the Dutch Pathological Society. University of Sheffield, UK.


K. Pettinger, A. Wright, L. Ward, D. Treanor & H. Grabsch (2012) The CD68+ macrophage to CD3+ T-cell ratio: a new independent prognostic marker in gastric cancer*. Presented at: Yorkshire and the Humber Postgraduate Deanery NHS Academic Foundation Presentation Day Programme. The Royal York Hotel, York, UK.


L Ruff, A Wright, L Ward, D Treanor, H Grabsch (2011) Tumour Infiltrating Lymphocytes and Prognosis in Gastric Carcinoma. Presented at: Yorkshire and the Humber Postgraduate Deanery NHS Academic Foundation Presentation Day Programme. The Royal York Hotel, York, UK.


A Wright, G Hutchins, R Randell, P Quirke, D Treanor (2010). TMAi (Tissue MicroArray informatics): Using virtual slides and open standards to provide usability and interoperability for tissue microarrays in clinical trials. Presented at: 6th NCRI Cancer Conference. BT Conference Centre, Liverpool, UK.


Wright A, Lander J, Kaushal S, Pan T, Sharma A, Wang F, Kurc T, Saltz J, Quirke P, Treanor D (2009). Utilising caGRID Infrastructure for Tissue MicroArray Analysis**. Presented at: Biomedical Informatics without borders: From collaboration to implementation. A joint conference of the U.S. National Cancer Institute and the U.K. National Cancer Research Institute Informatics Initiative. Wellcome Trust, London, UK.


Wright A, Lyttleton O, Lewis P, Quirke P, Treanor D (2009). TMAi | An open source Tissue Microarray database using published XML standards. Presented at: Biomedical Informatics without borders: From collaboration to implementation. A joint conference of the U.S. National Cancer Institute and the U.K. National Cancer Research Institute Informatics Initiative. Wellcome Trust, London, UK.


Lyttleton O, Wright A, Treanor D, Quirke P, Lewis P D (2009). Extending the Tissue Microarray Data Exchange Specification for inclusion of data analysis results. Presented at: Biomedical Informatics without borders: From collaboration to implementation. A joint conference of the U.S. National Cancer Institute and the U.K. National Cancer Research Institute Informatics Initiative. Wellcome Trust, London, UK.


Bennett A, Zhu Y, Wright A, Verbeke C, Hodgkin L, Magee D, Spiers V, Treanor D (2009). A novel nuclear detection algorithm for the automatic analysis of immunohistochemistry staining. Presented at: Joint Meeting of the Pathological Society of Great Britain and Ireland and the Dutch Pathological Society. University of Cardiff, UK.


Pan T, Treanor D, Wright A, Lander J, Waterhouse M, Kaushal S, Schmidt J, Harmer T, Gurcan M, Sharma A, Saltz J, Quirke P (2008). Utilizing caGrid Infrastructure for Pathology Image Analysis. Presented: at NCRI Informatics - caBIG Joint Conference: Biomedical Informatics without borders. Hyatt Regency, Bethesda, Maryland, USA.


Wright A, Magee D, Quirke P, Treanor D (2008). Automated scoring of Tissue Mircoarrays using virtual slides. Presented at: Joint Meeting of the Pathological Society of Great Britain and Ireland and the Dutch Pathological Society. University of Leeds, UK.



*Recipient of Best Poster Award
**Recipient of Best Poster Award (http://www.cancerinformatics.org.uk/jointconference_09.html)
***Recipient of 3rd Prize